Library.
3 verifications about Caenorhabditis Elegans Caenorhabditis Elegans ×
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True 10/10
“Caenorhabditis elegans SID-2 is required for intestinal uptake of ingested double-stranded RNA.”
SID-2 is required for intestinal uptake of ingested double-stranded RNA in Caenorhabditis elegans. Genetic studies show that animals lacking SID-2 resist RNA interference from ingested dsRNA but remain sensitive to injected dsRNA. Subsequent uptake experiments directly support SID-2’s role in importing ingested dsRNA into intestinal cells.
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Mostly True 7/10
“Bacterially produced double-stranded RNA is consumed by Caenorhabditis elegans and enters the endogenous RNA interference pathway to reduce expression of the corresponding target gene.”
Bacterially produced double-stranded RNA is ingested by Caenorhabditis elegans and triggers target-specific gene knockdown through the worm’s own RNAi machinery. Primary feeding experiments and uptake studies support this mechanism. The wording “endogenous RNA interference pathway” is technically loose: ingested dsRNA triggers exogenous RNAi, which shares components with distinct endogenous RNAi pathways.
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True 9/10
“WormBase and WormBook provide information on Caenorhabditis elegans gene function, mutant strains, developmental biology, and experimental methodologies.”
WormBase and WormBook collectively cover all four stated areas of C. elegans research. Peer-reviewed descriptions document WormBase's gene-function and mutant-strain information, while WormBook provides developmental-biology reviews and experimental protocols through WormMethods. Their complementary coverage supports the claim.